Background and Methods. The effect of intensive lipid-lowering therapy on coronary
atherosclerosis among men at high risk for cardiovascular events was assessed by quantitative …

OBJECTIVE: The anterior cingulate cortex has been implicated in depression. Results are
best interpreted by considering anatomic and cytoarchitectonic subdivisions. Evidence …

Background Early life stress (ELS) can compromise development, with higher amounts of
adversity linked to behavioral problems. To understand this linkage, a growing body of …

Structural models of credit risk provide poor predictions of bond prices. We show that, despite
this, they provide quite accurate predictions of the sensitivity of corporate bond returns to …

Major depression is a heterogeneous condition, and the search for neural correlates specific
to clinically defined subtypes has been inconclusive. Theoretical considerations implicate …

THE role of the amygdala in major depression was investigated. Resting regional cerebral
metabolic rate (rCMR glu) was measured with [18 F] fluorodeoxyglucose positron emission …

Lesion and neuroimaging studies suggest the amygdala is important in the perception and
production of negative emotion; however, the effects of emotion regulation on the amygdalar …

Increased activity of the epigenetic modifier EZH2 has been associated with different cancers.
However, evidence for a functional role of EZH2 in tumorigenesis in vivo remains poor, in …

Purpose in life predicts both health and longevity suggesting that the ability to find meaning
from life’s experiences, especially when confronting life’s challenges, may be a mechanism …

The relationships between brain electrical and metabolic activity are being uncovered currently
in animal models using invasive methods; however, in the human brain this relationship …