Artificial intelligence (AI) aims to mimic human cognitive functions. It is bringing a paradigm
shift to healthcare, powered by increasing availability of healthcare data and rapid progress …

… 2), showing prolonged circulation in the blood at time points of up to 72 h. … in lysosomes,
whereas uncoated particles were trapped within endolysosomal compartments after 24 h. …

… (c) Mössbauer spectra of MEA subjected to an oxidizing treatment of increasing length
between 1 h and 24 h. (d) Changes in the iron concentration and (e) mass activity measured …

We performed an extensive immunogenomic analysis of more than 10,000 tumors comprising
33 diverse cancer types by utilizing data compiled by TCGA. Across cancer types, we …

Population isolates such as those in Finland benefit genetic research because deleterious
alleles are often concentrated on a small number of low-frequency variants (0.1% ≤ minor …

Determining the genetic basis of cancer requires comprehensive analyses of large collections
of histopathologically well-classified primary tumours. Here we report the results of a …

We have profiled promoter DNA methylation alterations in 272 glioblastoma tumors in the
context of The Cancer Genome Atlas (TCGA). We found that a distinct subset of samples …

Genetic alterations in signaling pathways that control cell-cycle progression, apoptosis, and
cell growth are common hallmarks of cancer, but the extent, mechanisms, and co-…

… The tissue was further enzymatically dissociated with 0.8 mg/ml HBSS Liberase Research
Grade (#05-401-119-001; Roche) and incubated at 37 C for 1 h, followed by mechanical …

Invasive lobular carcinoma (ILC) is the second most prevalent histologic subtype of invasive
breast cancer. Here, we comprehensively profiled 817 breast tumors, including 127 ILC, …