Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
…, M Nizzari, SB Gabriel, GW Chirn, Q Ma, H Parikh… - Science, 2007 - science.org
New strategies for prevention and treatment of type 2 diabetes (T2D) require improved insight
into disease etiology. We analyzed 386,731 common single-nucleotide polymorphisms (…
into disease etiology. We analyzed 386,731 common single-nucleotide polymorphisms (…
Classification of SAR and PolSAR images using deep learning: A review
Advancement in remote sensing technology and microwave sensors explores the applications
of remote sensing in different fields. Microwave remote sensing encompasses its benefits …
of remote sensing in different fields. Microwave remote sensing encompasses its benefits …
A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22. 1, 1q32. 1 and 5p15. 33
…, JB Mendelsohn, DS Michaud, H Parikh… - Nature …, 2010 - nature.com
We conducted a genome-wide association study of pancreatic cancer in 3,851 affected
individuals (cases) and 3,934 unaffected controls drawn from 12 prospective cohort studies and …
individuals (cases) and 3,934 unaffected controls drawn from 12 prospective cohort studies and …
[HTML][HTML] The vaginal microbiome and preterm birth
…, JP Brooks, DJ Edwards, PH Girerd, HI Parikh… - Nature medicine, 2019 - nature.com
The incidence of preterm birth exceeds 10% worldwide. There are significant disparities in
the frequency of preterm birth among populations within countries, and women of African …
the frequency of preterm birth among populations within countries, and women of African …
[HTML][HTML] TXNIP regulates peripheral glucose metabolism in humans
H Parikh, E Carlsson, WA Chutkow… - PLoS …, 2007 - journals.plos.org
Background Type 2 diabetes mellitus (T2DM) is characterized by defects in insulin secretion
and action. Impaired glucose uptake in skeletal muscle is believed to be one of the earliest …
and action. Impaired glucose uptake in skeletal muscle is believed to be one of the earliest …
Impact of an exercise intervention on DNA methylation in skeletal muscle from first-degree relatives of patients with type 2 diabetes
…, S Lang, H Parikh, Y Wessman, H Weishaupt… - Diabetes, 2012 - Am Diabetes Assoc
To identify epigenetic patterns, which may predispose to type 2 diabetes (T2D) due to a
family history (FH) of the disease, we analyzed DNA methylation genome-wide in skeletal …
family history (FH) of the disease, we analyzed DNA methylation genome-wide in skeletal …
[HTML][HTML] Ultrasonographic soft markers of aneuploidy in second trimester: are we lost?
Chromosomal abnormalities occur in 0.1% to 0.2% of live births, and the most common
clinically significant aneuploidy among live-born infants is Down syndrome (trisomy 21). Other …
clinically significant aneuploidy among live-born infants is Down syndrome (trisomy 21). Other …
Tribology of fiber reinforced polymer matrix composites—A review
The use of fiber reinforced polymer matrix composites (FRPCs) is in boom in many structural,
industrial, automotive, and engineering applications. Polymer matrix composites have …
industrial, automotive, and engineering applications. Polymer matrix composites have …
[PDF][PDF] A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets
Close to 50 genetic loci have been associated with type 2 diabetes (T2D), but they explain
only 15% of the heritability. In an attempt to identify additional T2D genes, we analyzed global …
only 15% of the heritability. In an attempt to identify additional T2D genes, we analyzed global …
An open resource for accurately benchmarking small variant and reference calls
Benchmark small variant calls are required for developing, optimizing and assessing the
performance of sequencing and bioinformatics methods. Here, as part of the Genome in a …
performance of sequencing and bioinformatics methods. Here, as part of the Genome in a …