The translocator protein (18 kDa) (TSPO) is localized primarily in the outer mitochondrial
membrane of steroid-synthesizing cells, including those in the central and peripheral nervous …

Progesterone is commonly considered as a female reproductive hormone and is well-known
for its role in pregnancy. It is less well appreciated that progesterone and its metabolite …

Progesterone and its metabolites promote the viability of neurons in the brain and spinal cord.
Their neuroprotective effects have been documented in different lesion models, including …

Gastric diseases, including peptic ulcer disease and gastric cancer, affect 10% of the world’s
population and are largely due to chronic Helicobacter pylori infection 1 , 2 , 3 . Species …

Electronic medical records (EMRs) are critical, highly sensitive private information in
healthcare, and need to be frequently shared among peers. Blockchain provides a shared, …

Progesterone is shown here to be produced from pregnenolone by Schwann cells in peripheral
nerves. After cryolesion of the sciatic nerve in male mice, axons regenerate and become …

Successful implementation of bone marrow transplantation for hematopoietic reconstitution
is limited by the lack of suitably HLA-matched donors and by the occurrence of graft-versus-…

Most antianxiety drugs (anxiolytics) work by modulating neurotransmitters in the brain.
Benzodiazepines are fast and effective anxiolytic drugs; however, their long-term use is limited by …

Some neurosteroids have been shown to display beneficial effects on neuroprotection in
rodents. To investigate the physiopathological significance of neurosteroids in Alzheimer’s …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by
progressive death of cortical and spinal motor neurons, for which there is no effective …