[HTML][HTML] BMP2 and TGF-β cooperate differently during synovial-derived stem-cell chondrogenesis in a dexamethasone-dependent manner

…, M Alini, C Lischer, H Schmal, EJ Kubosch… - Cells, 2019 - mdpi.com
Recent studies highlighting mesenchymal stem cell (MSC) epigenetic memory suggest that
a different differentiation medium may be required depending on the tissue of origin. As …

[HTML][HTML] Preclinical ex-vivo Testing of Anti-inflammatory Drugs in a Bovine Intervertebral Degenerative Disc Model

Z Li, Y Gehlen, F Heizmann, S Grad, M Alini… - … in bioengineering and …, 2020 - frontiersin.org
Discogenic low back pain (LBP) is a main cause of disability and inflammation is presumed
to be a major driver of symptomatic intervertebral disc degeneration (IDD). Anti-inflammatory …

[HTML][HTML] Effect of expansion media and fibronectin coating on growth and chondrogenic differentiation of human bone marrow-derived mesenchymal stromal cells

V Basoli, E Della Bella, EJ Kubosch, M Alini… - Scientific Reports, 2021 - nature.com
In the field of regenerative medicine, considerable advances have been made from the
technological and biological point of view. However, there are still large gaps to be filled …

[HTML][HTML] Evaluation of the influence of platelet-rich plasma (PRP), platelet lysate (PL) and mechanical loading on chondrogenesis in vitro

N Pötter, F Westbrock, S Grad, M Alini, MJ Stoddart… - Scientific Reports, 2021 - nature.com
The aim of this work is to investigate the capability of PRP as an adjuvant therapy to
autologous chondrocyte implantation (ACI) in combination with multi-axial load with respect to …

[CITATION][C] Principles of Fixed-Income Securities Auctions

EJ Alini, PJ Elmer, F Raiter - The Journal of Fixed Income, 1995 - pm-research.com
FRANK RAITER is managing director at Standard & Poor’s in New York. He was chief of
securities sales in the capital markets department of the Resolution Trust Corporation at the time …

[PDF][PDF] The tissue-renin-angiotensin-system of the human intervertebral disc

Z Li, L Wystrach, A Bernstein, S Grad, M Alini… - Eur Cell …, 2020 - freidok.uni-freiburg.de
Symptomatic intervertebral disc (IVD) degeneration accounts for significant socioeconomic
burden. Recently, the expression of the tissue renin-angiotensin system (tRAS) in rat and …

The potential of chitosan-based gels containing intervertebral disc cells for nucleus pulposus supplementation

…, E DesRosiers, F Mwale, J Antoniou, M Alini - Biomaterials, 2006 - Elsevier
The suitability of chitosan-based hydrogels as scaffolds for the encapsulation of intervertebral
disc (IVD) cells and the accumulation of a functional extracellular matrix mimicking that of …

Are animal models useful for studying human disc disorders/degeneration?

M Alini, SM Eisenstein, K Ito, C Little, AA Kettler… - European Spine …, 2008 - Springer
Intervertebral disc (IVD) degeneration is an often investigated pathophysiological condition
because of its implication in causing low back pain. As human material for such studies is …

In vitro and in vivo evaluation of a novel nanosize hydroxyapatite particles/poly (ester-urethane) composite scaffold for bone tissue engineering

MW Laschke, A Strohe, MD Menger, M Alini, D Eglin - Acta biomaterialia, 2010 - Elsevier
Scaffolds for bone tissue engineering should provide an osteoconductive surface to promote
the ingrowth of new bone after implantation into bone defects. This may be achieved by …

Physical stimulation of chondrogenic cells in vitro: a review

S Grad, D Eglin, M Alini… - Clinical Orthopaedics and …, 2011 - journals.lww.com
Background Mechanical stimuli are of crucial importance for the development and
maintenance of articular cartilage. For conditioning of cartilaginous tissues, various bioreactor …