Long recognized as an evolutionarily ancient cell type involved in tissue homeostasis and
immune defense against pathogens, macrophages are being re-discovered as regulators of …

The proto-oncogene receptor tyrosine kinase ROS was originally discovered through the
identification of oncogenic variants isolated from tumors. These discoveries spearheaded a …

The Extracellular RNA Communication Consortium (ERCC) was launched to accelerate
progress in the new field of extracellular RNA (exRNA) biology and to establish whether …

Glioblastomas shed large quantities of small, membrane-bound microvesicles into the
circulation. Although these hold promise as potential biomarkers of therapeutic response, their …

In this article, we show that, in transfected COS-1 cells, protein tyrosine phosphatase (PTP)-PEST
translocates to the membrane periphery following stimulation by the extracellular …

Glioblastoma (GBM) is an incurable primary malignant brain cancer hallmarked with a
substantial protumorigenic immune component. Knowledge of the GBM immune …

Activation of the phosphatidylinositol 3-kinase (PI3K)/AKT signaling pathway is a frequent
occurrence in human cancers and a major promoter of chemotherapeutic resistance. Inhibition …

Glioblastoma multiforme (GBM) is a highly lethal brain tumor for which little treatment is
available. The epidermal growth factor receptor (EGFR) signaling pathway is thought to play a …

Background: The intake of trans fatty acids (TFA) from industrially hydrogenated vegetable
oils (iTFA) is known to have a deleterious effect on cardiovascular health, the effects of TFA …

Mouse embryos genetically null for all αv integrins develop intracerebral hemorrhage owing
to defective interactions between blood vessels and brain parenchymal cells. Here, we have …