User profiles for A. X. Zhang
Amy X. ZhangAssistant Professor, Computer Science & Engineering, University of Washington Verified email at cs.uw.edu Cited by 2338 |
Antibody-recruiting molecules: an emerging paradigm for engaging immune function in treating human disease
PJ McEnaney, CG Parker, AX Zhang… - ACS chemical …, 2012 - ACS Publications
Synthetic immunology, the development of synthetic systems capable of modulating and/or
manipulating immunological functions, represents an emerging field of research with …
manipulating immunological functions, represents an emerging field of research with …
Proteolysis‐targeting chimeras in drug development: a safety perspective
K Moreau, M Coen, AX Zhang, F Pachl… - British journal of …, 2020 - Wiley Online Library
Proteolysis‐targeting chimeras are a new drug modality that exploits the endogenous ubiquitin
proteasome system to degrade a protein of interest for therapeutic benefit. As the first‐…
proteasome system to degrade a protein of interest for therapeutic benefit. As the first‐…
Reduced default mode network functional connectivity in patients with recurrent major depressive disorder
…, AX Zhang, H Zhang, KR Zhang… - Proceedings of the …, 2019 - National Acad Sciences
Major depressive disorder (MDD) is common and disabling, but its neuropathophysiology
remains unclear. Most studies of functional brain networks in MDD have had limited statistical …
remains unclear. Most studies of functional brain networks in MDD have had limited statistical …
Tabletop x-ray ghost imaging with ultra-low radiation
AX Zhang, YH He, LA Wu, LM Chen, BB Wang - Optica, 2018 - opg.optica.org
Computational ghost imaging, in which an image is retrieved from a known patterned field
that illuminates an object and the total transmitted intensity therefrom, has seen great …
that illuminates an object and the total transmitted intensity therefrom, has seen great …
[HTML][HTML] Disrupted intrinsic functional brain topology in patients with major depressive disorder
…, AX Zhang, H Zhang, KR Zhang, L Zhang… - Molecular …, 2021 - nature.com
Aberrant topological organization of whole-brain networks has been inconsistently reported
in studies of patients with major depressive disorder (MDD), reflecting limited sample sizes. …
in studies of patients with major depressive disorder (MDD), reflecting limited sample sizes. …
How do data science workers collaborate? roles, workflows, and tools
Today, the prominence of data science within organizations has given rise to teams of data
science workers collaborating on extracting insights from data, as opposed to individual data …
science workers collaborating on extracting insights from data, as opposed to individual data …
[HTML][HTML] Diminished Schwann cell repair responses underlie age-associated impaired axonal regeneration
…, K Duong, CM Miller, S Posada, EJ Cobos, AX Zhang… - Neuron, 2014 - cell.com
The regenerative capacity of the peripheral nervous system declines with age. Why this occurs,
however, is unknown. We demonstrate that 24-month-old mice exhibit an impairment of …
however, is unknown. We demonstrate that 24-month-old mice exhibit an impairment of …
A remote arene-binding site on prostate specific membrane antigen revealed by antibody-recruiting small molecules
AX Zhang, RP Murelli, C Barinka, J Michel… - Journal of the …, 2010 - ACS Publications
Prostate specific membrane antigen (PSMA) is a membrane-bound glutamate carboxypeptidase
overexpressed in many forms of prostate cancer. Our laboratory has recently disclosed …
overexpressed in many forms of prostate cancer. Our laboratory has recently disclosed …
Exploring lightweight interventions at posting time to reduce the sharing of misinformation on social media
When users on social media share content without considering its veracity, they may
unwittingly be spreading misinformation. In this work, we investigate the design of lightweight …
unwittingly be spreading misinformation. In this work, we investigate the design of lightweight …
A structured response to misinformation: Defining and annotating credibility indicators in news articles
The proliferation of misinformation in online news and its amplification by platforms are a
growing concern, leading to numerous efforts to improve the detection of and response to …
growing concern, leading to numerous efforts to improve the detection of and response to …